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Carter Edwards
Carter Edwards

Download 2021 MySugr - Diabetes App Blood Sugar Tr...

Your doctor will want to check your feet at least annually to detect any signs of trouble with circulation, nerve damage, or the overall condition of your feet. Smoking and high blood sugar levels can significantly affect the health of your feet.

Download mySugr - Diabetes App Blood Sugar Tr...

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Kidneys are remarkable organs that remove waste products from the blood system. Diabetes can damage the kidneys and cause them to lose the ability to filter out waste products; which can result in kidney disease and kidney (renal) failure. Keeping your diabetes and blood pressure under control lowers the risk of kidney disease. A urine test known as albuminuria checks how well your kidneys are functioning and should be done once a year.

The beneficial effects of vitamin E may be explained by the reduction of the damaging effects of free radicals on the structural and functional components of cells and vessel walls [56, 57]. It is believed that diabetes is associated with increased oxidative stress because of increased blood concentrations of thiobarbituric acid reactive substances and serum malondialdehyde, the end products of lipid peroxidation [58]. The adverse physiological effects which result include increased leakiness of cell membranes where the structural integrity of membranes has been altered; inactivation of membrane bound enzymes and surface receptors and the involvement of oxidized LDL (LDL-ox). When total antioxidant status (TAC) is high enough to combat the oxidative stress, the MDA and TBARS levels are in the normal limits and vice versa. Antioxidants decrease the oxidative damage directly by reacting with free radicals or indirectly by inhibiting the activity or expression of free radicals [59, 60].

In the literature, vitamin D is related to gene expression control which may trigger a biological response to oxidative stress, such as inhibiting nitric oxide synthase (iNOS) or increasing glutatione levels [66]. The antioxidant effect of vitamin D is among the most recent non-calcemic roles suggested for this compound [67]. There is evidence from both humans and animal models suggesting that vitamin D may play an important role in modifying the risk of diabetes [66, 68]. Low vitamin D status is associated with future macrovascular events in patients with T2DM. This association may be the result of the link between vitamin D status and the renin-angiotensin system, endothelial function, blood pressure, or even chronic inflammation [20, 69, 70]. However, our results were constrained in defining a vitamin D antioxidant profile, since few RCTs involving this micronutrient were included [43, 44]. 041b061a72


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